Justin Bieber - Avalanna Routh, aka “Mrs. Bieber

The 6-year-old girl, who Justin Bieber and his fans referred to as “Mrs. Bieber,” died Wednesday morning.

just got the worst news ever,” Justin tweeted after learning the news. “one of the greatest spirits i have ever known is gone. please pray for her family and for her. … RIP Avalanna. i love you”

Avalanna Routh, aka “Mrs. Bieber,” was adored nationwide for her brave struggle with a rare and incurable cancer called AT/RT and of course her unending love for the teen pop star.

“Our darling Avalanna went to Heaven this morning,” her family wrote on Twitter. “Oh Avalanna, the brightest star — you took our hearts with you, our greatest love.”

Avalanna hit headlines in February when she got the gift of a lifetime, a date with her beloved idol.

Bieber learned about the young girl after her family started a “Get Avalanna to Meet Justin Bieber” campaign on Facebook and Twitter, using the hashtag, #MrsBieber. Avalanna was so infatuated with the singer her nurses once organized a pretend wedding, where Avalanna “married” a cardboard cutout of Bieber.

Bieber flew his cancer-stricken fan and her mother to New York for an early Valentine’s Day date, where they played board games and snacked on cupcakes and candy. He later tweeted the date was “one of the best things I have ever done.”

Dr. Charles Robert of the Dana-Farber Cancer Institute told The Associated Press Avalanna was diagnosed with cancer when she was 18 months old.

Our thoughts go out to Avalanna Routh’s family.

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